As the portal from the famous “three” viagra-cialis-levitra showed therapeutic efficacy against very severe genetic disease of Duchenne muscular dystrophy. For the pilot study followed a large-scale clinical trials.
In a pilot test of drugs commonly used for the treatment of erectile dysfunction in a new way – to treat a severe form of muscular dystrophy was attended by 10 boys, patients with Duchenne muscular dystrophy.
However, the organizers plan before the end of this year to begin a larger scale test involving at least 300 patients from different countries – so promising were the results.
Duchenne muscular dystrophy affects only males (boys – as the disease begins to appear in childhood).
In this disease due to genetic mutations is the gradual destruction of nerve-muscle connections, there is a deterioration of blood supply to the muscles.
The best of the currently used drugs for the treatment of Duchenne muscular dystrophy show an efficiency of only 75% of patients.
For this reason, the discovery of previously unknown possibilities of two drugs from the Arsenal of sexologists may significantly improve the results of treatment of such patients.
American scientists from the research center cedars-Sinai in Los Angeles (Cedars-Sinai Institute in Los Angeles) once injected 5 boys aged 8 to 13 years, suffering from Duchenne muscular dystrophy, the drug sildenafil, better known under the trade name viagra.
Another 5 patients of the same age were administered the drug tadalafil (cialis) is a medication that is also used for the treatment of impotence.
Study of the level of blood supply to the muscles of patients showed that both are the drug increases the blood flow in the vessels of the muscles by an average of 60% after some physical exertion. And during the control study after physical activity without the introduction of drugs an increase in blood flow was only 32%.
The authors believe that improving the blood supply to the muscle is able to significantly slow them in the dystrophic process.